Team — UCSF Immunoprofiler

Autoimmunoprofiler tEAM

Project ADMINISTRATION & Leadership

Matthew 'Max' Krummel, PhD Principal Investigator Max is an immunologist whose lab uses live-imaging to find key pathways in biology. He has a rich history at the immune-cancer interface incl… — **Matthew 'Max' Krummel, PhD**
*Principal Investigator*
Max is an immunologist whose lab uses live-imaging to find key pathways in biology. He has a rich history at the immune-cancer interface including as the developer of anti-CTLA-4 (ipilimumab/Yervoy) therapeutics. He maintains an active lab that studies the fundamentals of how the immune system functions dynamically in space and time and how cell types integrate to generate fundamental immune states. His current work in mice identified immune cell subsets in tumors that provide initial signatures to develop within the UCSF Immunoprofiler.

Jeroen Roose, PhD Co-Investigator AutoimmunoprofilerDr. Roose is a tenured Principal Investigator and Vice Chair of Anatomy at the University of California, San Francisco. He is also a co-founder of UCSF's ImmunoX. The Roose lab studies the impact … — **Jeroen Roose, PhD**
*Co-Investigator Autoimmunoprofiler*
Dr. Roose is a tenured Principal Investigator and Vice Chair of Anatomy at the University of California, San Francisco. He is also a co-founder of UCSF's ImmunoX. The Roose lab studies the impact Ras-kinase signals have on cell fate decisions in health and disease. By taking a collaborative approach working with biophysicists, computational engineers, geneticists, and many clinicians, the Roose research team spans the gamut from fundamental science to pre-clinical trials

Jimmie Ye, PhD Co-Investigator AutoimmunoprofilerDr. Ye is an associate professor in the Department of Medicine at the University of California, San Francisco. The Ye lab is interested in how the interaction between genetics and environment affect … — **Jimmie Ye, PhD**
*Co-Investigator Autoimmunoprofiler*
Dr. Ye is an Associate Professor in the Department of Medicine at the University of California, San Francisco. The Ye lab is interested in how the interaction between genetics and environment affect human variation at the level of molecular phenotypes. To study these interactions, the lab couples high-throughput sequencing approaches that measure cellular response under environmental challenges with population genetics where such measurements are collected and analyzed across large patient cohorts.

Vincent Chan, PhD Senior Scientist/Project ManagerVincent manages the entire UCSF Immunoprofiler Consortium and focuses on colorectal analytics. He was initially trained as a biological engineer in 3D bioprinting and tissue engineering at MIT and Un… — **Vincent Chan, PhD**
*Senior Scientist/Project Manager*
Vincent manages the entire UCSF Immunoprofiler Consortium and focuses on colorectal analytics. He was initially trained as a biological engineer in 3D bioprinting and tissue engineering at MIT and University of Illinois, Urbana-Champaign, but changed his professional career when his mother was diagnosed with rectal cancer. He oversees all aspects of the consortium and actively participates in analytics and data mining.

Nora Hazenbos-Shibata
Project Manager

Nora is the Project Manager for the UCSF Autoimmunoprofiler Initiative. In this position, she ensures the study team achieves the project objectives. This includes coordinating sample pipelines, monitoring project progress, and strategic planning to meeting project goals. She received her Bachelor’s degree in Neurobiology at UC Berkeley.

Gabriela Fernandez-Cuervo, PhD
Strategic Alliance Manager

Gabriela develops strategic corporate partnerships on behalf of UCSF, identifying new strategic partners to complement UCSF's translational research pipeline through pre-clinical studies. Within the UCSF Immunoprofiler Consortium, she manages the industry alliances and identifies new partners and collaborators. She received her Ph.D. in Pharmaceutical Sciences with a focus on Drug Discovery and Development from the University of Arizona and continued her postdoctoral training at Stanford University School of Medicine.

Alexis Combes, PhD Disease 2 Biology DirectorOriginally from France with a PhD in immunology from the Centre d’ Immunologie de Marseille-Luminy (CIML) in Marseille, Alexis is the Disease to Biology (D2B) CoLab director and project manager for Immuno… — **Alexis Combes, PhD**
*Disease 2 Biology Director*
Originally from France with a PhD in immunology from the Centre d’ Immunologie de Marseille-Luminy (CIML) in Marseille, Alexis is the Disease to Biology (D2B) CoLab director and project manager for Immunoprofiler. D2B is a collaboration-based research lab that focuses on profiling the immune system in various set of diseases. The Disease to biology CoLab is responsible for running assays to profile samples that are part of the Immunoprofiler consortium. Prior to joining CoLabs, Alexis was a postdoctoral researcher in Max Krummel lab where he used multi omics approaches to describe immune tumor archetypes using the immunoprofiler data.

**Gabriela Fragiadakis, PhD**
*Data Science CoLab Director*
Gabriela is an Assistant Professor at UCSF. She leads a computational immunology lab studying states of the human immune system across disease contexts using single-cell methods and data integration. Through CoLabs, she established partnerships to study systems-level immunity in viral infection, cancer, autoimmunity, and steady-state. Her work is in immune phenotypes across contexts using high-dimensional analysis, data integration, and novel computational methods.

Andrew Gross, MD
Co-Investigator Autoimmunoprofiler

Dr. Gross, a Rheumatologist, is Co-Director of the UCSF Scleroderma Center and Medical Director of Rheumatology at UCSF. Gross's research investigates the causes of scleroderma. He collaborates with immunology researchers at UCSF to seek new treatments for scleroderma, which they believe will be discovered by better understanding how cells of the immune system become deregulated.